Sarah Lauder

Sarah Lauder

Company: Cardiff University

Job title: Research Associate


Sequential Targeting of PI3Kd & LAG-3 as an Effective Anti- Cancer Approach 12:45 pm

Immunomodulation by PI3Kδ-blockade led to tumor regressor and nonregressor mice, with complete control of tumor burden reliant on: (1) the dampening of a Treg response and (2) the generation of an improved antigen-specific CD8 response Differences in Treg phenotype delineated which mice displayed tumor regression, with non-regressor tumors significantly enriched with cells expressing the coinhibitory…Read more

day: Day Two

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