Sarah Lauder
Company: Cardiff University
Job title: Research Associate
Seminars:
Sequential Targeting of PI3Kd & LAG-3 as an Effective Anti- Cancer Approach 12:45 pm
Immunomodulation by PI3Kδ-blockade led to tumor regressor and nonregressor mice, with complete control of tumor burden reliant on: (1) the dampening of a Treg response and (2) the generation of an improved antigen-specific CD8 response Differences in Treg phenotype delineated which mice displayed tumor regression, with non-regressor tumors significantly enriched with cells expressing the coinhibitory…Read more
day: Day Two