Andrew Pierce

Andrew Pierce

Company: Crescendo Biologics

Job title: Vice President - Translational Biology


Panel Discussion: Tug of War: Understanding How LAG-3 & PD-1 Interplay with One Another 9:30 am

What are the key learnings and questions that have come out of the RELATIVITY-047 Trial? How do we rationally test PD-1/LAG-3 combinations in a way that further elucidates their interplay with one another? Will our understanding grow more in vivo with mice, or in the clinic?Read more

day: Day Two

Primary Pharmacology of CB213, a LAG-3-PD1 Co-targeting Humabody™ 2:00 pm

CB213 is engineered to engage LAG-3 particularly on PD1 expressing cells Human ex vivo and mouse syngeneic in vivo studies illustrate CB213 anti-tumor activity Pharmacokinetics studies in non-human primates suggest weekly or biweekly clinical dosing of CB213Read more

day: Day One

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